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Relationship between disturbance of intestinal flora and postoperative cognitive function and postoperative complications after valve replacement under cardiopulmonary bypass

Relationship between disturbance of intestinal flora and postoperative cognitive function and postoperative complications after valve replacement under cardiopulmonary bypass

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029222
Enrollment
Unknown
Registered
2020-01-19
Start date
2020-01-13
Completion date
Unknown
Last updated
2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive function

Interventions

case series:N/A

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 55 years old who underwent valve replacement in West China Hospital of Sichuan University signed an informed consent form.

Exclusion criteria

Exclusion criteria: Preoperative diagnosis of intestinal diseases or autoimmune diseases; preoperative cognitive function changes or infection; preoperative diagnosis of systemic diseases, such as malignant tumor, metabolic syndrome, impairment of liver and kidney function and other chronic consumptive diseases; continuous use of glucocorticoids within half a year before operation or massive use of glucocorticoids within 1 month before operation; Antibiotics were used within three months before operation (except routine prophylactic use) or had a history of operation within half a year.

Design outcomes

Primary

MeasureTime frame
cognitive function;—

Countries

China

Contacts

Public ContactLiang Peng

West China Hospital of Sichuan University

liangpeng@wchsu.cn+86 18980602201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026