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Propofol combined with different concentrations of remifentanil for painless gastroscopy: a randomized controlled clinical study

Propofol combined with different concentrations of remifentanil for painless gastroscopy: a randomized controlled clinical study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029216
Enrollment
Unknown
Registered
2020-01-19
Start date
2020-02-01
Completion date
Unknown
Last updated
2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia

Interventions

control group:propofol
experiment group 1:propofol and 1.25ug/ml remifentail
experiment group 2:propofol and 2.5ug/ml remifentail
experiment group 3:propofol and 5ug/ml remifentail

Sponsors

The Affiliated Hospital of Nantong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult outpatients undergoing elective gastroscopy and sedated with propofol were enrolled in this study.

Exclusion criteria

Exclusion criteria: (1) coagulation disorders attendency for nose bleeding; (2) an episode/exacerbation of congestive heart failure that required a change in medication, diet, or hospitalization from any cause in the last 6 months; (3) severe aortic stenosis or mitral stenosis; (4) cardiac surgery involving thoracotomy (eg, coronary artery bypass graft or valve replacement surgery) in the last 6 months; (5) acute myocardial infarction in the last 6 months; (6) acute arrhythmia (including tachycardia and bradycardia) with hemodynamic instability; (7) diagnosed chronic obstructive pulmonary disease (COPD) or other current acute or chronic lung diseases requiring sup-plemental chronic or intermittent oxygen therapy; (8) increased intracranial pressure; (9) America Society of Anesthesiologists (ASA) class >III; (10) mouth, nose, or throat infection; (11) fever, defined as core body temperature >37.5 degree C; (12) pregnancy, breastfeeding, or positive pregnancy test; and (13) emergency procedure.

Design outcomes

Primary

MeasureTime frame
Dose of propofol;

Secondary

MeasureTime frame
Incidence of hypoxia;Recovery time;

Countries

China

Contacts

Public ContactChaochao Zhong

The Affiliated Hospital of Nantong University

zhong24967626@163.com+86 15152460489

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026