Perioperative liver injury
Conditions
Interventions
Case series:None
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years old, male or female; 2. Patients who need to undergo hepatectomy (resection volume is limited to three or more liver segments); 3. Participate voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Intraoperative hepatectomy was not performed; 2. Complicated with heart, lung, renal insufficiency and other systemic diseases; 3. Patients with severe hypokalemia and hypernatremia; 4. Those who are allergic to the ingredients of glycyrrhizin preparations; 5. Pregnancy and lactation; 6. Participants in other clinical trials within 3 months; 7. Plan to use liver-protecting drugs with the same or similar composition as monoammonium glycyrrhizinate and sodium chloride injection; 8. The researcher considered that the patient was not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total recovery rate of liver function in subjects receiving hepatoprotective therapy after hepatectomy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total effective rate of liver function recovery in different primary patients;The total recovery rate of liver function using different combinations of hepatoprotective drugs;The total effective rate of liver function recovery in different surgical methods; | — |
Countries
China
Contacts
Public ContactBao-Gang Peng
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed