Solid Tumors
Conditions
Interventions
Sponsors
Beijing Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 year; ECoG 0 or 1; 2. patients with histologic confirmed HER2 positive breast cancer, gastric cancer or other tumors or suspected tumors who are to undergo pathological biopsy or tumor surgical treatment (within 2 months); 3. life expectancy >=12 weeks; 4. Blood routine test and liver and kidney function criteria: blood routine test: WBC >=4.0x10^9/L or neutrophil >= 1.5x10^9/L, PLT >=100x10^9/L, Hb >=90g/L; Pt or APTT <=1.5 ULN; liver and kidney function: T-Bil <=1.5 ULN, ALT / AST <=2.5 ULN or <=5 ULN (subjects with liver metastasis), ALP <=2.5 ULN (if there is bone metastasis or liver metastasis, ALP <=4.5 ULN); bun <=1.5 ULN, SCR <=1 .5 ULN; 5. With at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1); 6. During the study period and 6 months after the end of the study, female patients must adopt effective contraceptive measures (effective contraceptive measures refer to sterilization, hormone device in the child's office, condom, contraceptive / agent, abstinence or partner's vasectomy, etc.); male patients should adopt contraceptive measures during the study period and 6 months after the end of the study period; 7. Able to understand and sign the informed consent with good compliance.
Exclusion criteria
Exclusion criteria: 1) Significant hepatic or renal dysfunction; 2) Pregnant or ready to pregnancy; 3) Cannot lie on their back for half an hour; 4) Refusal to join the clinical study; 5) Suffering from claustrophobia or other mental diseases; 6) Any other situation that researchers think it is not suitable to participate in the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactZhu Hua
Beijing Cancer Hospital
Outcome results
None listed