Hypospadias in children
Conditions
Interventions
Group H1 (hydromorphone group 1):Hydromorphone 0.1mg/kg + flurbiprofen ester 5mg / kg
Group H2 (hydromorphone group 2):Hydromorphone 0.2mg/kg + flurbiprofen ester 5mg / kg
Group C (sufentanil group):Sufentanil 1.5ug/kg
Sponsors
Xiamen Maternal and Child Care Hospital
Eligibility
Sex/Gender
Male
Age
0.5 Years to 3 Years
Inclusion criteria
Inclusion criteria: 1) Aged 6 months to 3 years; 2) ASA I, or II in the children who were to be general anesthesia by tracheal intubation; 3) Children who have abdominal surgery (open or laparoscopic), orthopedic surgery, facial features surgery and urology surgery; 4) The parent or legal guardian of the child has signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Those who are allergic to flurbiprofen ester, hydromorphone hydrochloride or its components, and children who have a history of opioid allergy; 2) 24 hours before the operation, analgesics, antiemetics, anti pruritus and quinolones were used; 3) Children with acute upper respiratory tract infection before operation; 4) Children with a history of asthma; 5) Children with severe sleep apnea syndrome and arrhythmia; 6) Previous abnormal operation anesthesia recovery history; preoperative evaluation of the presence or possible presence of difficult airway; 7) Renal function damage (BUN and / or Cr > the upper limit of normal value), liver function damage (ALT and / or ast > 1.5 times the upper limit of normal value); 8) It is difficult to evaluate the analgesic effect of children with related mental and neurological diseases; 9) Children with a history of chronic pain or taking painkillers for a long time; 10) Children with severe obesity or preterm infants less than six months of corrected age 11) Patients with other conditions considered unsuitable by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative FLACC score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation Ramsay score; | — |
Countries
China
Contacts
Public ContactJia Junxiang
Xiamen Maternal and Child Care Hospital
Outcome results
None listed