Effects of post-hospital developmental care on neurodevelopment and epigenetic modification of brain-derived neurotrophic factor gene (BDNF) in preterm infants

Developmental care for preterm infants with brain injury: model construction, effect demonstration and epigenetic regulation of BDNF gene

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029185

Enrollment

Unknown

Registered

2020-01-17

Start date

2020-03-09

Completion date

Unknown

Last updated

2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm birth

Interventions

Experimental group:developmental care

Control group:Conventional care

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. premature infants with gestational age between 28 and 37 weeks who were admitted to the neonatal intensive care unit within 1 week; 2. the main caregivers are permanent residents of wuhan and its surrounding areas, and they can regular follow-up. 3. the primary caregivers volunteered to participate in the whole research process

Exclusion criteria

Exclusion criteria: 1. Preterm infants suffer from genetic and metabolic diseases or congenital malformations; 2. Preterm infant with grade iii-iv intracerebral hemorrhage; 3. The main caregivers have mental, cognitive and verbal communication disorders, or substance abuse.

Design outcomes

Primary

Measure	Time frame
neurodevelopment;	—

Countries

China

Contacts

Public ContactJun Zhang

Wuhan University

1528161351@qq.com+86 18507118605

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026