heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female patients aged 18-70 years. 2. Time of CPB is expected to last more than 2 hours in patients undergoing cardiac surgery. 3. Patients with complete preoperative examination, laboratory examination, etiological examination, medical record and medical history. 4. Patients who understand the objectives of this study, and are willing to sign informed consent files by themselves or their legal representatives.
Exclusion criteria
Exclusion criteria: 1. Poor compliance, difficult to follow. 2. with severe cerebrovascular disease, liver and kidney dysfunction, immune system disease, severe trauma . 3. severe anemia with hemoglobin content <80 g/l. 4. coagulation disorderplatelet count<100x10^9/l. 5. Psychiatric disorders; 6. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| free hemoglobin;granule membrane glycoprotein of platelet (GMP140);Platelet Factor 4;Tissue Factor;thrombomodulin;F1+ 2;d-dimer;TAT;AT?;complications;postoperative hospital stay;postoperative icu retention time;mechanical ventilation time; | — |
Countries
China
Contacts
Tianjin Chest Hospital