Metabolism of Iron , folic acid, vitamin E
Conditions
Interventions
Nutrient high risk group:Supplementary nutrients
Nutrient low risk group:Supplementary nutrients
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Early gestation (within 13 weeks); 2. Able to receive regular prenatal examination and delivery in participating research units, and obtain perinatal outcome data; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant women who taken medications that severely interfere with folate, iron, vitamin E or lipid absorption, metabolism, and utilization from three months before pregnant to the time of inclusion; 2. Pregnant women who taken medications of folate, iron, vitamin E ,but couldnt provide accurate information on the species and dose; 3. with history of major surgery, trauma or major organ disease; 4. with long term medication history; 5. with serious mental behavior disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SNP detection of iron metabolism-related gene polymorphisms;SNP detection of folic acid metabolism-related gene polymorphisms;SNP detection of vitamin E metabolism-related gene polymorphisms;Pregnancy outcomes;Iron, folic acid, vitamin E biochemical indicators; | — |
Countries
China
Contacts
Public ContactLiu Yan-ping
Peking Union Medical College Hospital
Outcome results
None listed