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Clinical study for assisted reproductive technology in orthotopic transplantation of autogenous ovarian tissue after activation of egg in vitro

Clinical study for assisted reproductive technology in orthotopic transplantation of autogenous ovarian tissue after activation of egg in vitro

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029148
Enrollment
Unknown
Registered
2020-01-16
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

DOR(diminished ovarian reserve)

Interventions

Case series:Laparoscopy after intervention

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Aged 20-40 years old, had menstrual history; 2. The menopause time was 0.5-5 years; 3. dFSH>=25IU/L 4. Bilateral ovaries could be seen under B-ultrasound, and there was no operation history of bilateral ovaries; 5. Can tolerate laparoscopic surgery; 6. Normal chromosome.

Exclusion criteria

Exclusion criteria: 1. Severe hypertension, diabetes, heart disease and other organic diseases can not tolerate surgery and pregnancy; 2. Chromosome abnormality; 3. History of bilateral ovarian surgery due to bilateral ovarian endometriosis; 4. Allergic to the related reagents used in the in vitro activation of follicles; 5. Patients with substantial ovarian lesions.

Design outcomes

Primary

MeasureTime frame
Number of eggs retrieved;Available embryo rate;Pregnancy rate;

Secondary

MeasureTime frame
AMH;AFC;

Countries

China

Contacts

Public ContactMa Ling

Zhongnan Hospital of Wuhan University

810323923@qq.com+86 18502729279

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026