COPD?asthma?bronchiectasis
Conditions
Interventions
Gold Standard:1.After inhalation of bronchodilator,FEV1 / FVC < 0.7, it was diagnosed as COPD
2. The patients with positive bronchodilation test or provocation test were diagnosed as asthma
3. The patient was previously diagnosed with bronchiectasis by HRCT
technology
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=14 years old; 2. The diagnosis of chronic obstructive pulmonary disease, asthma or bronchiectasis was made in the past; 3. There was no history of acute exacerbation in one month.
Exclusion criteria
Exclusion criteria: 1. Patients with digestive tract diseases or hyperlipidemia, hyperglycemia and hypertension; 2. Patients with acute exacerbation or antibiotic use within 4 weeks; 3. Patients who have received systemic glucocorticoid treatment within 4 weeks; 4. Patients with active tuberculosis; 5. Pregnant women; 6. Alcoholism and drug abuse; 7. Patients who can not complete the required research procedures due to any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pulmonary function;FENO;Blood routine;chest CT scan;metabonomics;transcriptomics;proteomics;Microbiome;immune repertoire;questionnaire;genomics;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactFuqiang Wen
West China Hospital, Sichuan University
Outcome results
None listed