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Randomized controlled trial for ultrasound-guided parasternal intercostal nerve block (PSB) reduces the amount of analgesics used in off-pump coronary bypass surgery

Ultrasound-guided parasternal intercostal nerve block (PSB) reduces the amount of analgesics used in off-pump coronary bypass surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029128
Enrollment
Unknown
Registered
2020-01-15
Start date
2020-02-03
Completion date
Unknown
Last updated
2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary atherosclerotic heart disease

Interventions

Experimental group 1:Bilateral pectoralis transverse plane block
Experimental group 2:Plane block of bilateral pectoralis major and intercostal muscles
Control group:Transverse transverse pectoralis with equal volume of saline

Sponsors

General Hospital of Northern Theater Command of the Chinese People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. NYHA I-III; 2. Patients undergoing off-pump coronary artery bypass graft surgery; 3. First open chest surgery; 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. Severe neurological symptoms such as stroke with sequelae; 3. Hemodynamic instability is defined as systolic blood pressure <90mmHg; 4. Place aortic balloon counterpulsation or ventricular assist device before surgery; 5. Preoperative severe liver and kidney dysfunction (dialysis patients with chronic renal failure or patients with child grade B or higher chronic liver disease); 6. Non-first thoracotomy; 7. Mediastinal fiber thickening or severe pleural adhesions; 8.Have severe systemic infection; 9. Infection at the nerve block; 10. Patients cannot cooperate with research, such as language understanding, mental illness, etc.; 11. Participated in other clinical trials within 3 months before enrollment.

Design outcomes

Primary

MeasureTime frame
Total Sufentanil Dosage During Operation;—

Secondary

MeasureTime frame
Nerve block operation time and block plane;Postoperative analgesic dose, postoperative pain score;Myocardial injury;Inflammation-related biomarkers;Stress related indicators;Postoperative mechanical ventilation time and ICU stay time;Hospitalization days;MACCE incidence at 30 days after surgery;Incidence of other complications at 30 days after surgery;30-day postoperative mortality;One year postoperative mortality;—

Countries

China

Contacts

Public ContactYingjie Sun

General Hospital of Northern Theater Command of the Chinese People's Liberation Army

sunyingjie9@hotmail.com+86 13940348767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026