Rectal Cancer single center prospective clinical study: Assessment of Neoadjuvant Chemoradiation Outcome based on Radiomics of Multiparametric MRI

The mechanism exploration research of difference in efficacy of chemoradiation based on the correlation analysis of the tumor microenvironment and multi-parametric magnetic resonance imaging in locally advanced rectal cancer

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000029101

Enrollment

Unknown

Registered

2020-01-13

Start date

2019-08-01

Completion date

Unknown

Last updated

2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

Gold Standard:pathology

Index test:MRI

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. The pathological diagnosis is rectal adenocarcinoma; 2. The stage is locally advanced; 3. All patients assessed by qualified Multiparametric MRI before treatment, received standard preoperative radiotherapy and chemotherapy, and havd complete surgical pathology.

Exclusion criteria

Exclusion criteria: 1. Multiparametric MRI is not qualified or not examined; 2. The preoperative chemoradiation therapy regimen is not the standard treatment; 3. No operation was acted after preoperative hemoradiation therapy or not acted in our center.

Design outcomes

Primary

Measure	Time frame
pCR prediction accuracy;SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactXiaonan Sun

SIR RUN RUN SHAW Hospital

sunxiaonan@hotmail.com+86 13606618387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026