Small cerebrovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients aged between 50 and 85 years old; 2. patients showed white matter hyperintensities on FLAIR MR images according to a revised version of the scale of Fazekas; 3. presence of a contactable informant throughout the study.
Exclusion criteria
Exclusion criteria: 1. cardiac or renal failure, cancer, or other severe systemic diseases; 2. unrelated neurological diseases such as epilepsy, traumatic brain injury and multiple sclerosis; 3. chronic cerebral infarction or other lesions; 4. leukoencephalopathy of non-vascular origin; 5. dementia of non-vascular origin; 6. psychiatric diseases or drug addiction; 7. consciousness disruption or aphasia; 8. inability or refusal to undergo brain MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognition score;The result of MRI; | — |
Countries
China
Contacts
Beijing Tiantan Hospital, Capital Medical University