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A multicentre cohort study for the effectiveness and necessity of prophylactic use of antibiotics for the prevention and treatment of postoperative complications such as infection after mandibular impacted third molars extraction

A multicentre cohort study for the effectiveness and necessity of prophylactic use of antibiotics for the prevention and treatment of postoperative complications such as infection after mandibular impacted third molars extraction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029091
Enrollment
Unknown
Registered
2020-01-12
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impacted mandibular third molar

Interventions

antibiotic use group:N/A
Without antibiotic use Group:N/A

Sponsors

West China School of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. The patients were aged between 18 and 40 (including) years. 2. The patient has at least one mandibular third molars that need to be extracted, and the impacted molar cannot be detected in the mouth. 3. Radiologic examination showed that the crown was embedded submucosa or bone, and the bone thickness above the crown was no more than 1mm. 4. The mouth opening and occlusion was right before operation. 5. The patient did not have relative or absolute contraindications of tooth extraction and could be received ordinary tooth extraction.

Exclusion criteria

Exclusion criteria: 1. Perioperative coronitis occurred within 15 days before tooth extraction; 2. Other unplanned drugs use during the follow-up period; 3. Patients taking hormones and painkillers after surgery; 4. Postoperative bleeding needs another operation; 5. Female patients got pregnant during follow-up period; 6. Unable or unwilling to complete the interview; 7. smoking history; 8. history of allergy.

Design outcomes

Primary

MeasureTime frame
postoperative swelling;postoperative pain;Interincisor Distance;dry socket;body temperature;local infection;

Countries

China

Contacts

Public ContactPan Jian

West China School of Stomatology, Sichuan University

jianpancn@163.com+86 13981805249

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026