Biomarkers for Neonatal Neuroinflammation: an Observational Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000029064

Enrollment

Unknown

Registered

2020-01-12

Start date

2020-02-10

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

meningitis/EOS/LOS

Interventions

central nervous system infection group vs. peripheral infection group:N/A

Eligibility

Sex/Gender

All

Age

No minimum to 1 Years

Inclusion criteria

Inclusion criteria: 1. Neonate is admitted at the participating departments of Neotatology. 2. Gestational age at delivery < 37 weeks. 3. CSF should be collected for clinical examination of newborn suspected meningitis. 4. Parenteral consent is signed by at least a parent agreeing that neonatal blood and CSF will be collected.

Exclusion criteria

Exclusion criteria: Major congenital abnormalities or birth defects.

Design outcomes

Primary

Measure	Time frame
Molecular markers of CSF associated with central nervous system damage due to infection;	—

Secondary

Measure	Time frame
Molecular markers of CSF associated with central nervous system inflammation due to peripheral infection;Molecular markers to distinguish between gram - negative and positive bacterial infections;	—

Countries

China

Contacts

Public ContactPingping Jiang

School of Public Health, Sun Yat-Sen University

jiangpp3@mail.sysu.edu.cn+86 13266595242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026