Study for Percutaneous Penetration Facilitated by Cold Atmospheric Plasma

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029063

Enrollment

Unknown

Registered

2020-01-12

Start date

2020-02-15

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

transdermal drug dlivery

Interventions

Experimental group:CAP pretreatment before topical lidocaine applied

Control group:no pretreatment before topical lidocaine applied

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. All races, sexes, and ethnicities; 2. Aged between 18 and 60 years; 3. Seeking full-face CO2 laser treatment for acne scarring

Exclusion criteria

Exclusion criteria: 1. Allergy to topical anesthetics; 2. Pregnancy or lactation; 3. Keloid or hypertrophic scar formation on face; 4. Any alteration in pain sensation; 5. Had microdermabrasion, severe sunburn, chemical peel, laser treatment, or other severe abrasions to the face/neck in the past 45 days; 6. Being treated with Accutane; 7. Had any disease causing abrasion or sloughing of skin of treatment area in the past 45 days; 8. History of heart arrhythmia, liver dysfunction, congestive heart failure, hypertension, chronic renal insufficiency, chronic renal failure, anxiety disorder, psychosis, or seizure.

Design outcomes

Primary

Measure	Time frame
pain VAS;	—

Countries

China

Contacts

Public ContactXiang Wen

West China Hospital, Sichuan University

xiangwen_wcums@163.com+86 15351200113

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026