Intestinal dysfunction
Conditions
Interventions
Experimental group:Enteral nutrition with short-peptide formulation
Control group:Enteral nutrition with total protein formulation
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. Organ failure needs intensive treatment and has nutritional risk; 3. A valid enteral nutrition tube has been established; 4. Digestive juice (gastric juice, bile, pancreatic juice) can be effectively used directly or indirectly; 5. No intestinal flora disturbance; 6. No diarrhea.
Exclusion criteria
Exclusion criteria: 1. Urgent treatment is needed for perforation, hemorrhage and intestinal obstruction of abdominal cavity organs; 2. Intestinal ischemia or enteroparalysis; 3. Short bowel syndrome; 4. Bleeding and shock have not been corrected; 5. Oral diet is available; 6. History diseases of inflammatory bowel disease, chronic pancreatitis and irritable bowel syndrome; 7. Pregnancy; 8. Absent of informed consent from patient or representative.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of enterogenous infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| intestinal flora disturbance;Bacterial enteritis or suspected bacterial enteritis;Feeding intolerance;New set of organ failure;The length of ICU stay;The length of hospital stay; | — |
Countries
China
Contacts
Public ContactJiang Ronglin
The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed