aspiration pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy adults Inclusion criteria: a. age 18-65; b. no history of respiratory tract infection in recent 8 weeks; c. no abnormality in physical examination, X-ray examination and blood routine examination; d. no history of smoking; e. no obvious oil smoke, dust, peculiar smell and special chemicals in working environment. 2. Patients with aspiration pneumonia Inclusion criteria: a. age 65 years year or older; b. clinical diagnosis of aspiration pneumonia, now C-reactive protein and all inflammatory indicators are turned negative for at least 3 months, the condition is stable; c. oral feeding.
Exclusion criteria
Exclusion criteria: 1. Healthy adults (1) have a history of chronic respiratory diseases, or have serious heart, liver, kidney and other systemic diseases; (2) have used ACEI, bronchodilator, hormone, antihistamine and antitussive drugs in recent 4 weeks. 2. Elderly patients with aspiration pneumonia (1) cognitive impairment, MMSE score less than 24 points; (2) previous stroke history or new stroke; (3) long-term tracheotomy; (4) smoking; (5) chronic respiratory disease history or serious heart, liver, kidney and other systemic diseases; (6) ACEI, bronchodilator, hormone, antihistamine and antitussive drugs have been used in recent 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough reflex threshold;urge-to-cough; | — |
Countries
China
Contacts
Beijing Friendship Hospital, Capital Medical University, Beijing, China