Central nerve system injury
Conditions
Interventions
control group:Routine rehabilitation
rTMS 1:Routine rehabilitation+rTMS (M1)
rTMS 2:Routine rehabilitation+rTMS (PMC+M1)
Sponsors
Department of rehabilitation medicine; Xijing Hospital of The Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Central nervous system injury, including brain injury and spinal cord injury; 2. Clinical diagnosis of neuropathic pain in line with the pain standard of International Association for the study of neuropathic pain; 3. Aged 18-70 years; 4. MEP can be recorded in the first dorsal interosseous; 5. No obvious cognitive impairment (MMSE > 22 points); 6. Signed by the patient or family member Department informed consent.
Exclusion criteria
Exclusion criteria: 1. It has the contraindications of rTMS (epilepsy, pregnancy, pacemaker, head metal implant); 2. The drugs currently used interact with rTMS; 3. History of mental illness; 4. Acute pain caused by other reasons; 5. Active malignant tumor; 6. It has been treated by rTMS in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS;SF-MPQ-2-CN;Brain-derived Neurotrophic Factor;Nerve growth factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Barthel Index, BI;Hamilton Anxiety Scale, HAMA;Neurophysiological detection;fNIRS; | — |
Countries
China
Contacts
Public ContactYuan Hua
Department of rehabilitation medicine; Xijing Hospital of The Fourth Military Medical University
Outcome results
None listed