ovarian failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients with benign lesions of factor uterus who need hysterectomy (preserving ovaries); 2) Aged 40-50 years old, serum E2, FSH, and LH were checked before the follicular phase, suggesting that ovarian function has not yet failed, AMH <1.1ng / ml; 3) Postoperative pathology confirmed benign uterine lesions; 4) No history of other hormone or sex hormone use within 3 months; 5) Those who agree to be inspected and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system, history of tumor, endocrine disease, and mental illness; 2) Those who fail to take medication as prescribed by the doctor, or have incomplete data, etc., which affect the judgment of efficacy; 3) Patients who are participating in other clinical trials or have participated in other clinical trials in the past month; 4) Other patients identified by the researcher as unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Follicle stimulating hormone (FSH);Kupperman score;Perimenopausal quality of life score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ovarian arterial blood flow parameters;Luteinzing hormone (LH);Estradiol (E2);Anti-mullerian hormone (AMH); | — |
Countries
China
Contacts
Changzhou No.2 People's Hospital