Interstitial lung disease
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient inclusion criteria: 1. Patients aged >=18 years; 2. Patients who meet the above-mentioned diagnostic criteria for SSc-ILD or PM / DM-ILD; 3. Sign the informed consent voluntarily. Inclusion criteria for healthy volunteers: 1. Aged 30-65 years old; 2. No asthma, COPD, bronchiectasis, tuberculosis, lung cancer and other lung diseases; no lung infection in the last 3 months 3. No systemic lupus erythematosus, Sjogren's syndrome, dermatomyositis, rheumatoid arthritis, scleroderma, gout, various vasculitis and other connective tissue diseases 4. No chronic diseases such as poor control and severe hypertension, diabetes, etc.
Exclusion criteria
Exclusion criteria: 1. Suffering from scleroderma-like diseases: such as renal-derived hard fibrosis, generalized scleroderma, eosinophilic fasciitis, scleredema, sclerosing myxedema, erythema, pain, porphyria, moss Sclerosis, graft versus host disease, and diabetic hand joint disease; 2. Subjects whose clinical connective tissue types changed after induced sputum collection; 3. Patients after lung transplantation; 4. Patients who cannot tolerate induced sputum manipulation; 5. Patients who cannot sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| metabolomic profile of induced sputum; | — |
Secondary
| Measure | Time frame |
|---|---|
| pulmonary function;Nutritional Index;Immune Index;complications; | — |
Countries
China
Contacts
Public ContactFengming Luo
West China School of Medicine, Sichuan University
Outcome results
None listed