Bullous Pemphigoid
Conditions
Interventions
experimental group:subclinical dosage of Cyclosporine, Prednisone or Methylprednisolone and Halometasone Cream.
control group:Prednisone or Methylprednisolone, Halometasone Cream
Sponsors
The First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age:18-64,both gender,blood routines and urine routines are normal,without the liver function lesion and kidney lesion; 2. Meet diagnostic criteria of moderate and severe bullous pemphigoid; 3. No immunosuppressants were used in the first 3 months and there are no contraindications for the use of cyclosporine; 4. Complete the whole study according to the requirements of the study and can follow up as required; 5. The informed consent has been signed and willing to complete the research process.
Exclusion criteria
Exclusion criteria: 1. Pregnancy,lactating mother,a woman of child-bearing age who has fertility requirements; 2. WBC < 3.5 x 10^9/L; 3. Severe liver and kidney damage; 4. There are contraindications to the use of glucocorticoids or cyclosporine; 5. Patients with bullous pemphigoid who have been treated and stable patient; 6. Patients who are currently participating in other clinical studies or who have participated in other clinical studies within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BP180;BP230; | — |
Countries
China
Contacts
Public ContactLi He
The First Affiliated Hospital of Kunming Medical University
Outcome results
None listed