Labor Pain
Conditions
Interventions
Sponsors
Women's Hospital of Nanjing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. ASA status I-II; 2. Aged 18-45 years; 3. Body mass index = 37 weeks; 5. Singleton, cephalic, primipara; 6. Epidural analgesia is required, and the cervical dilatation < 3cm; 7. Understand pain scale and Edinburgh depression scale; 8. Those who have not used opioids and other sedative analgesics, and have not used magnesium sulfate; 9. No abnormal fetal heart rate monitoring before labor analgesia (fetal heart rate range 110-160bpm).
Exclusion criteria
Exclusion criteria: 1. Contraindications to neuraxial anesthesia (eg, abnormal coagulation function, infection at puncture site); 2. Those who have difficulty performing epidural procedures (such as scoliosis and ankylosing spondylitis); 3. Allergic to known research drugs 4. Those who use sedative, hypnotic and analgesic drugs within one week 5. History of drug abuse 6. History of sleep apnea syndrome 7. Patients with severe heart, lung, liver, and kidney dysfunction 8. History of bronchial asthma; 9. Combined with pregnancy-related diseases such as hypertension, gestational diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consumption of ropivacaine per hour; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain score;The frequency and effective frequency of patient-controlled analgesia;additional rescues;Consumption of opioid per hour;Overall pain score during labor;Patient satisfaction;the second stage of labor;the first stage of labor;Oxytocin consumption;mode of delivery;Apgar scores;umbilical artery blood gases;Fetal heart rate;NICU admission; | — |
Countries
China
Contacts
Public ContactYao Zhang
Women's Hospital of Nanjing Medical University
Outcome results
None listed