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Effects of different doses of nalbuphine combined with propofol for digestive endoscopy on the concentration of propofol

Effects of different doses of nalbuphine combined with propofol for digestive endoscopy on the concentration of propofol

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029003
Enrollment
Unknown
Registered
2020-01-11
Start date
2020-01-13
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive diseases

Interventions

group A:Nabuphine 0.05mg/kg slow intravenous bolus for more than 30s
group B:Nabuphine 0.1mg/kg slow intravenous bolus for more than 30s
group C:Nabuphine 0.15mg/kg slow intravenous bolus for more than 30s

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients planning to undergo painless gastroscopy or enteroscopy; 18-65 years old, no gender restriction; Body Mass Index (BMI) 18.5 ~ 30 kg / m2; American Society of Anesthesiologists (ASA) grade I ~ III.

Exclusion criteria

Exclusion criteria: Patients with severe liver and kidney dysfunction; those who are allergic to emulsions and opioids; those who cannot cooperate without communication.

Design outcomes

Primary

MeasureTime frame
Vomiting response during gastroscope insertion;Body movement;

Secondary

MeasureTime frame
Induction time;Eyes open time;Total propofol dosage;Satisfaction score;

Countries

China

Contacts

Public ContactXiao Weimin

Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

529719950@qq.com+86 13871118432

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026