sepsis
Conditions
Interventions
Case series:no
Sponsors
Chinese PLA general hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: ICU admission patients who simultaneously meet all the following conditions will be included: 1. aged >=18 years old; 2. sign the informed consent; 3. for patients with infection or suspected infection, sepsis related sequential organ failure (SOFA) score >=2; 4. the presence of confirmed or suspected infection foci shall meet at least one of the following criteria: (1) growth of diseased microorganisms in blood or sterile areas; (2) abscesses or the presence of partially infected tissues; (3) suspected infection supported by at least one of the following evidence: 1) white blood cells in normal sterile sites; 2) visceral perforation (imaging evidence, examination results, or intestinal content leakage caused by drainage); 3) imaging evidence of pneumonia accompanied by purulent secretion; 4) high risk of infection-related syndrome (such as: cholangitis, etc.).
Exclusion criteria
Exclusion criteria: Patients will be excluded if they meet any of the following criteria: 1. Length of stay in ICU < 48h or possible death within the next 24 hours; 2. if a person decides to stop or cancel artificial life support, that is, to give up treatment; 3. refuse to participate in this study or participate in other clinical trials within 2 months; 4. unable to tolerate or cooperate with the treatment of endo-pat due to physical reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| reactive hyperemic index; | — |
Secondary
| Measure | Time frame |
|---|---|
| hematological examination;28-day mortality;Acute physical and chronic health assessment II score;Sequential organ failure assessment score;EQ-5D scoring scale;Infection index; | — |
Countries
China
Contacts
Public ContactFeihu Zhou
Chinese PLA general hospital
Outcome results
None listed