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Prospective clinical research of radiofrequency catheter septal ablation for hypertrophic obstructive cardiomyopathy

Prospective clinical research of radiofrequency catheter septal ablation for hypertrophic obstructive cardiomyopathy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028976
Enrollment
Unknown
Registered
2020-01-10
Start date
2020-02-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertrophic obstructive cardiomyopathy

Interventions

Ablation group:endocardial radiofrequency ablation of septal hypertrophy

Sponsors

Xiamen University Affiliated Cardiovascular Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years old (inclusive) male or female. 2. Hypertrophic obstructive cardiomyopathy, obstruction of left ventricular outflow tract (obstruction: LVOTG >= 30mmHg at rest; latent obstruction: normal LVOTG at rest, LVOTG >= 30mmHg at stress exercise), with obstruction-related clinical symptoms (such as syncope, amaurosis, dyspnea, chest pain). 3. The patient is willing to follow up and agree to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with intracardiac thrombus or ventricular incision or atrial incision in the past four weeks; 2. Patients using prosthetic valves; 3. Patients with systemic active infections; 4. For patients with left atrial thrombus, myxoma, atrial septal defect surgery, atrial transeptal puncture is banned; 5. For patients undergoing aortic valve replacement surgery, retrograde aortic approach surgery is prohibited; 6. Patients with significant bleeding tendency or bloody diseases; 7. Patients with malignant tumors or end-stage diseases; 8. Pregnant women.

Design outcomes

Primary

MeasureTime frame
left ventricular outflow tract gradient;

Countries

China

Contacts

Public ContactDong Chang

Xiamen University Affiliated Cardiovascular Hospital

cdheart@126.com+86 18098875761

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026