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Target blood pressure management during cardiopulmonary bypass improves postoperative lactic acid levels: a randomized controlled clinical study

Target blood pressure management during cardiopulmonary bypass improves postoperative lactic acid levels: a randomized controlled clinical study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028941
Enrollment
Unknown
Registered
2020-01-08
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlactic

Interventions

MAP50-60mmHg group:with or without vasoactive drugs
MAP70-80mmHg group:maintaining blood pressure with norepinephrine

Sponsors

Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiaotong University,
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Selective heart valve surgery; 2. Aged > 18 years; 3. NYHAC II-III; 4. EF> 50%; 5. Blood lactate level <1.6 mmol / L; 6. Alanine transferase (ALT) <50U / L; 7. Brain natriuretic peptide (BNP) <100pg / ml; 8. Stay overnight in ICU after surgery.

Exclusion criteria

Exclusion criteria: 1. Secondary aortic occlusion during the operation; 2. Emergency surgery again within 24H after the operation.

Design outcomes

Primary

MeasureTime frame
Blood lactate value;—

Countries

China

Contacts

Public ContactWu Jingxiang

Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiaotong University

wjx1132@163.com+86 18930857186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026