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Effects of different Glucose-Insulin-Potassium regimes on blood glucose and potassium concentration in different types of surgery.

Effects of different Glucose-Insulin-Potassium regimes on blood glucose and potassium concentration in different types of surgery.

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028938
Enrollment
Unknown
Registered
2020-01-08
Start date
2020-01-13
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar surgery,partial hepatectomy

Interventions

2:1:Insulin 20iu and potassium chloride 2g in 400 mL of 10% glucose
4:1:Insulin 10iu and potassium chloride 1g in 400 mL of 10% glucose
3:1:Insulin 13iu and potassium chloride 1.3g in 400 mL of 10% glucose

Sponsors

Department of Anesthesia, the Second Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Elective lumbar surgery and partial hepatectomy in the second Xiangya Hospital requiring general anesthesia; 2. Aged 18 to 65 years; 3. Written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients receiving medications known to affect glucose or potassium homeostasis; 2. Patients with previously diagnosed blood glucose > 180mg/dl(10mmol/L) or 5.5mmol/L or <3.0mmol/L; 3. Patients with previously diagnosed diabetes; 4. Patients with previously diagnosed renal insufficiency or major heart disease; 5. Patients with syndromes associated with any derangements in the outcome measures; 6. Patients with a long history of high dose of steroids; 7. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Blood glucose;Blood glucose;Blood potassium;

Secondary

MeasureTime frame
Heart rate;Mean arterial pressure;Arrhythmia;Heart arrest;Catecholamine dosage;ALT;AST;Surgical morbidity;Length of stay;

Countries

China

Contacts

Public ContactRuping Dai

Department of Anesthesia, the Second Xiangya Hospital of Central South University

xyeyyrupingdai@csu.edu.cn+86 18974924753

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026