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The molecular prediction model guided the clinical cohort study of early non-squamous non-small cell lung cancer postoperative survival decisions

The molecular prediction model guided the clinical cohort study of early non-squamous non-small cell lung cancer postoperative survival decisions

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000028931
Enrollment
Unknown
Registered
2020-01-08
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-squamous non-small cell lung cancer

Interventions

Case Series:Nil

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Primary lung cancer; 2. Stage I to IV non-squamous non-small cell lung cancer (in which stage Ia to Ib patients accounted for at least 50 % of the total); 3. The patient is under 75 years old (included 75 years old); 4. Formalin fixed paraffin-embedded cancer tissues and the matched para-cancer tissues were preserved after complete surgical resection; at least 10 tissue sections are provided, and the tumor occupies greater than 25 % of the tissue surface area.

Exclusion criteria

Exclusion criteria: 1. Received treatment (included radiotherapy, chemotherapy, targeted therapy and immunotherapy) before surgery; 2. Tissue missing or inadequate tissue blocks (ie, the tumor that occupies < 25 % of the tissue surface area; or the sample quality does not meet the requirements of subsequent experiments (ie sample degradation)); 3. Death within 30 days of resection; 4. Positive margins on pathology; 5. A second cancer (excluding cutaneous basal and squamous-cell carcinomas) diagnosed within 3 years of the lung cancer diagnosis.

Design outcomes

Primary

MeasureTime frame
progression free survival;

Countries

China

Contacts

Public ContactYanhui Wan

Shenzhen Second People's Hospital

wisewyh@163.com+86 13510139611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026