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Efficacy of combined multiple nerve block on postoperative pain and functional outcome after total knee arthroplasty: a prospective, double-blind, randomized controlled trial

Efficacy of combined multiple nerve block on postoperative pain and functional outcome after total knee arthroplasty: a prospective, double-blind, randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028877
Enrollment
Unknown
Registered
2020-01-05
Start date
2018-10-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee

Interventions

A:Adductor canal block + IPACK block
B:Adductor canal block + IPACK block + obturator nerve block
C:Adductor canal block + IPACK block + obturator nerve block+ lateral femoral cutaneous nerve block

Sponsors

Department of Orthopaedics Surgery, West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients requiring unilateral initial TKA surgery due to severe knee osteoarthritis; 2. aged 40 to 80 years; 3. body mass index 20~35 kg/m2; 4. the American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level.

Exclusion criteria

Exclusion criteria: 1. allergic to anesthetic drugs and sulfa; 2. there were more than moderate intraoperative knee malformations (pronation and flexion malformations) and joint stiffness; 3. alcoholic or long-term opioid users; 4. language impairment and inability to perform pain numerical scales (NRS); 5. surgical limb neuropathy; 6. mental patients; 7. patients with previous gastrointestinal ulcer.

Design outcomes

Primary

MeasureTime frame
Postoperative dosage of remedial morphine hydrochloride;Time of first postoperative analgesia;VAS pain score;QoR -15 scale;Range of knee motion;Quadriceps strength;Daily walking distance;Time to first straight leg raise;The duration of hospital stay;Incidence of postoperative complications;

Countries

China

Contacts

Public ContactPengde Kang

West China Hospital, Sichuan University

kangpengd@163.com+86 13281896910

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026