Cirrhosis
Conditions
Sponsors
Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Diagnosis PBC can be determined by having 2 of the following 3 items: (1) Serum anti mitochondrial antibody was positive; (2) The level of serum ALP and / or ? - glutamyltranspeptidase increased; (3) The typical pathological changes of non suppurative cholangitis and interlobular bile duct injury were found in liver histology.
Exclusion criteria
Exclusion criteria: Exclusion criteria of PBC group: (1) the intrahepatic and extrahepatic bile ducts have space occupying lesions or obstruction; (2) viral hepatitis, alcoholic hepatitis, drug-induced liver injury and liver cancer; (3) infectious diseases and cardiovascular diseases; (4) hypertension, diabetes and malignant tumor; (5) receiving immunosuppressive drugs or enhancer drugs; (6) autoimmune hepatitis, primary sclerosing cholangitis and overlapping syndrome of autoimmune liver disease; (7) other autoimmune diseases. In order to avoid the influence of drugs on serum FFA spectrum, all the subjects should exclude the use of drugs (no drugs used in the past 2 months).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum free fatty acid;ALP;GGT;RNA of; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;sex; | — |
Countries
China
Contacts
Public ContactYang Jinhui
Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed