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The analgesic efficacy of Pregabalin and NSAID in Postoperative Acute Pain following Total Knee Arthroplasty.

The analgesic efficacy of Pregabalin and NSAID in Postoperative Acute Pain following Total Knee Arthroplasty: a prospective study design?for randomized, double-blind controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028868
Enrollment
Unknown
Registered
2020-01-05
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Knee arthroplasty

Interventions

A:Pregabalin
B:Celecoxib
C:Combine of Pregabalin and Celecoxib

Sponsors

West China Hospital, Sichuan University .
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. VAS Score >=7; 2. Eligibility aged between 18-80 years; 3. Elective surgeries; 4. ASA <=3.

Exclusion criteria

Exclusion criteria: 1. Allergic to Pregabalin or NSAID drugs; 2. Coagulopathies, CNS & CVS disorders; 3. Renal & hepatic comorbidities; 4. Immuno-compromised patients; 5. History of gastrointestinal diseases.

Design outcomes

Primary

MeasureTime frame
Pain;PONV;Clinical and functional outcome;Total cost and length of hospital stay;—

Countries

China

Contacts

Public ContactDr. Zong-Ke Zhou

Department of Orthopaedics, West China Hospital, Sichuan Universit

zongke@126.com+86 028 85422570

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026