Aspiration pneumonia
Conditions
Interventions
Aspiration pneumonia vs. Non Aspiration pneumonia:N/A
Sponsors
The Second Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: (1) Intensive unit inpatients who aged 18 years or older and whose stroke onset time was within 72 hours. (2) All included patients met the diagnostic criteria for acute ischemic stroke: Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018. 1) acute onset; 2) focal neurological deficits (weakness or numbness of one side of the face or limb, speech disorder, etc.) and a minority of total neurological dysfunction; 3) imaging lesions or symptoms and signs lasted more than 24 hours; 4) exclude non-vascular causes; 5) exclude cerebral hemorrhage by brain CT/MRI. Diagnostic criteria for acute hemorrhagic stroke: Chinese Guidelines for the Diagnosis and Treatment of Intracerebral Hemorrhage 2014: 1) acute onset; 2) focal neurological deficit symptoms (a small number of total neurological dysfunction) which was often accompanied by headache, vomiting, elevated blood pressure and varying degrees of disturbance of consciousness; 3) head CT or MRI showed bleeding lesions; 4)exclusion of non-vascular causes of the brain. (3) Diagnostic criteria for stroke-associated pneumonia (SAP): Diagnosis of stroke-associated pneumonia – Expert group consensus on stroke complicated with pneumonia 2015: 1) Clinical diagnosis: new or progressive pulmonary infiltrative lesions after stroke, complicated with more than two clinical symptoms: fever >= 38 degree C; new cough, expectoration, purulent discharge, with or without chest pain; signs of lung consolidation, and/or wet rales; peripheral blood leukocytes >= 10 x 10^9/L or <= 4 x 10^9/L, with or without nuclear shift to the left; 2) Etiological diagnosis: The deep sputum was sucked out from the sputum suction tube of patients with tracheal intubation/air tube incision, and the samples are taken for examination. (4) All participants signed the Informed Consent Form for Human Research in the Second Affiliated Hospital of Zhejiang University School of Medicine.
Exclusion criteria
Exclusion criteria: (1) patients with infectious diseases (including pneumonia) within 3 months before the onset of stroke. (2) patients who have used antibiotics within 3 months. (3) patients complicated with chronic obstructive pulmonary disease, interstitial lung disease, lung tumor, atelectasis, pulmonary edema, pulmonary embolism and autoimmunity diseases. (4) previous history of dysphagia or gastroesophageal reflux. (5) pregnant. (6) patients imaging of the lung did not accord with the manifestations of pneumonia after discussion by the research team. (7) patients whose medical records are incomplete or cannot provide accurate medical history and medication history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pneumonia;infectious incicators;sputum microbss;mechanical ventilation time;length of ICU stay;length of hospital stay;ICU mortality;hospital mortality; | — |
Countries
China
Contacts
Public ContactTian Baoping
The Second Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed