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Study for the relationship between LXR, IDH and primary biliary cholangitis

LXR and IDH regulate Foxp3 / ROR?t axis and participate in the pathogenesis of PBC

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000028803
Enrollment
Unknown
Registered
2020-01-04
Start date
2020-01-06
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis

Interventions

PBC:none

Sponsors

Second Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Elevated hepatic obstruction enzyme; 2. The pathological features of liver were consistent with the changes of PBC; 3. Serum AMA-M2 antibody positive.

Exclusion criteria

Exclusion criteria: 1. Tumor patients; 2. Combined with multiple diseases; 3. Combined with other liver diseases.

Design outcomes

Primary

MeasureTime frame
LXR;IDH;SREBP2;FOXP3;ROR?t;Foxp3 methylation degree;Grade of liver inflammation;IL-17A;TNF-alpha;—

Secondary

MeasureTime frame
sex;Age;ALP;GGT;—

Countries

China

Contacts

Public ContactYang Jinhui
17787003686@163.com+86 13608712810

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026