A randomized controlled clinical trial of methylprednisolone in improving postoperative delirium in elderly patients with gastrointestinal surgery

Protective effect of methylprednisolone on postoperative delirium in elderly patients undergoing gastrointestinal surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000028792

Enrollment

Unknown

Registered

2020-01-04

Start date

2020-01-06

Completion date

Unknown

Last updated

2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

Group M:methylprednisolone

Group P:Saline

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective gastrointestinal surgery under general anesthesia; 2. Aged 65-80 years; 3. ASA grades II to III; 4. Surgery with an estimated operation time within 2-6 hours.

Exclusion criteria

Exclusion criteria: 1. Patients with dementia (MMSE 8mmol / L); 6. Hct <28% before surgery; 7. history of cerebral hemorrhage or cerebral infarction (within 3 months); 8. patients with Parkinson's disease; 9. previous digestion Patients with canal ulcers; 10. identified / suspected of abuse of narcotic sedative analgesics.

Design outcomes

Primary

Measure	Time frame
Plasma related indicators;delirium score;	—

Secondary

Measure	Time frame
Pain score;Hemodynamics;Adverse reactions;	—

Countries

China

Contacts

Public ContactXiang Xiaobing

Department of Anesthesiology, Zhejiang Cancer Hospital

237607488@qq.com+86 18258112726

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026