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A single-center prospective randomized controlled trial for comparing the efficacy of laparoscopic hepatectomy with open hepatectomy in the treatment of hepatic alveolar echinococcosis

A single-center prospective randomized controlled trial for comparing the efficacy of laparoscopic hepatectomy with open hepatectomy in the treatment of hepatic alveolar echinococcosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028783
Enrollment
Unknown
Registered
2020-01-04
Start date
2020-02-01
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatic alveolar echinococcosis

Interventions

1:Laparoscopic hepatectomy
2:Open hepatectomy

Sponsors

The State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Preoperative diagnosis of hepatic alveolar echinococcosis by abdominal ultrasound and/or abdominal CT; 2. Aged 14 to 60 years; 3. Preoperative liver function Child grade A or B; 4. The lesion was confined to the hemihepatic region, and the healthy liver had sufficient compensatory volume; 5. Number of hepatic veins invaded by lesions <=2; 6. The lesion did not invade the inferior vena cava; 7. The number of lesions invading portal vein <=1 branch; 8. The lesion did not invade the diaphragm; 9. No distant metastasis of the lesion occurred in brain or lung; 10. The lesion size should not exceed 10 cm; 11.PNM stage P1~2N0~1MO 12. No serious organic diseases of heart, lung or brain, American anesthesiology society grade i-iii; 13. Subjects are able to understand the study contents of this project and voluntarily sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients refused to participate in the clinical trial; 2. Unwilling to undergo hepatectomy for various reasons; 3. Surgical contraindication and intolerance; 4. Primary liver diseases complicated with cirrhosis and liver cancer; 5. Complicated with malignant tumors of other organs, or with a history of liver metastasis of malignant tumors of other organs; 6. Patients with a history of hepatectomy; 7. Transfer to open for various reasons during the operation; 8. Postoperative pathology confirmed that it was not hepatic alveolar echinococcosis; 9. Poor patient compliance, or failure to adhere to visitors for various reasons, or pregnant and nursing women.

Design outcomes

Primary

MeasureTime frame
Intraoperative blood loss, incision size, intraoperative blood transfusion amount, whether intraoperative lesions residue, postoperative exhaust time, postoperative liquid diet for the first time for the first time time, ambulation, for the first time after time, postoperative pain, for the first time tolerance time, postopera;

Secondary

MeasureTime frame
Operation time, operation cost, total cost of hospitalization;

Countries

China

Contacts

Public ContactWen Hao

The State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia

dr.wenhao@163.com+86 13609933113

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026