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A randomized, controlled trial for evaluating the efficacy and safety of oseltamivir in the treatment of ulcerative colitis

A randomized, controlled trial for evaluating the efficacy and safety of oseltamivir in the treatment of ulcerative colitis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028767
Enrollment
Unknown
Registered
2020-01-03
Start date
2020-04-27
Completion date
Unknown
Last updated
2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ulcerative colitis

Interventions

Experimental group:Oseltamivir and mesalazine

Sponsors

Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 yeas old; 2. mild to moderate active ulcerative colitis patients; 3. can understand the whole process of this research and sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients currently using biologic agents; 2. Patients currently using glucocorticoids more than 25mg/d; 3. Patients allergic to salicylic acid; 4. Patients with creatinine clearance less than 60ml/min; 5. Patients who cannot understand and cooperate with the researcher,for example,Patient with severe mental illness, drug or alcoholic abuse; 6. Patients with active infection in intestine 7. Woman in pregnancy or lactation; 8. Patients with diabetes 9. Had participated in any other clinical investigator within 1 month prior to our screening visit.

Design outcomes

Primary

MeasureTime frame
Complete remission rate;

Secondary

MeasureTime frame
Clinical response rate;improvement of biochemical indicators;Clinical symptom score;Endoscopic score;Histopathological score;

Countries

China

Contacts

Public ContactXiaowei Liu

Xiangya Hospital of Central South University

liuxw@csu.edu.cn+86 13548762632

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 11, 2026