cervical and lumbar radiculopathy
Conditions
Interventions
Gold Standard:Clinical outcome
Index test:DTI-MRI 
and 
electromyography
Sponsors
Jiangsu Province Hospital on Integration of Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Diagnostic criteria for cervical spondylotic radiculopathy: (1) typical nerve root symptoms (numbness and pain in the arm), and the location is consistent with the area of cervical spinal nerve; (2) positive for neck compression test or brachial plexus traction test; (3) imaging findings were consistent with clinical manifestations; (4) no obvious effect of pain point injection (this test is not required if the diagnosis is clear); (5) excluding diseases mainly caused by upper limb pain caused by external cervical spine lesions (thoracic outlet syndrome, tennis elbow syndrome, carpal tunnel syndrome, cubital tunnel syndrome, periarthritis of shoulder, biceps tendon inflammation, etc.); 2. The criteria for the diagnosis of lumbar disc herniation: (1) unilateral or bilateral nerve root injury or cauda equina syndrome symptoms; (2) signs: unilateral or bilateral positive signs of nerve root injury or cauda equina damage; (3) imaging examination: intervertebral disc herniation or prolapse compressed nerve root or cauda equina nerve; 3. The criteria for the diagnosis of lumbar stenosis: (1) chronic low back pain; (2) long-term and repeated lumbago and leg pain and intermittent claudication. The lumbago is alleviated in forward flexion and aggravated in backward extension; (3) lower limb muscular atrophy, weakened tendon reflex and positive lumbar dorsal extension test; (4) CT/MRI examination indicated lumbar degeneration and spinal stenosis. The diagnosis should combine symptoms, signs and imaging examination, and exclude other diseases; 4. The systematic conservative treatment failed after 2 months; 5. The course of disease was less than 2 months, but MRI showed obvious nerve root compression, the patient had severe symptoms and actively required surgical treatment; 6. Aged 18 and 80 years; 7. Informed consent, volunteer subjects.The process of obtaining informed consent shall comply with GCP requirements. The patients who meet the inclusion criteria 4-7 and one of 1-3 can be included.
Exclusion criteria
Exclusion criteria: 1. Spinal tumors, infections, tuberculosis and skin conditions do not permit surgery; 2. Spinal instability with diseased segments; 3. There is contraindicated evidence of MR examination; 4. Pregnant and nursing women; 5. Persons who are unable to give full informed consent due to mental or behavioral disabilities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DTI;DTI;electromyography; | — |
Countries
China
Contacts
Public ContactZhipeng Xi
Jiangsu Province Hospital on Integration of Chinese and Western Medicine
Outcome results
None listed