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Randomized Comparison of Intrathecal Morphine Versus Standard Therapy on Post-Caesarean Delivery Quality of Recovery

Randomized Comparison of Intrathecal Morphine Versus Standard Therapy on Post-Caesarean Delivery Quality of Recovery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000028730
Enrollment
Unknown
Registered
2020-01-01
Start date
2020-05-04
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parturients

Interventions

Placebo group:Intrathecal saline 0.1ml
morphine group:intrathecal morphine 0.1ml

Sponsors

Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Elective cesarean delivery under single shot spinal anesthesia; 2. Lower segment cesarean delivery with planned Pfannestiel incision; 3. ASA (American Society of Anesthesiologists) Class 1 to 2; 4. Aged >=18 years old; 5. Willing and able to give consent.

Exclusion criteria

Exclusion criteria: 1. Emergency cesarean delivery; 2. Indication for additional post-operative analgesics on top of usual departmental regime (e.g. classical cesarean, pre-eclampsia, post-partum hemorrhage); 3. Contraindicated to paracetamol or diclofenac (e.g. allergy, renal or liver impairment, asthma, peptic ulcer disease); 4. Allergic to morphine.

Design outcomes

Primary

MeasureTime frame
QoR-15 Questionnaire;

Secondary

MeasureTime frame
American Pain Society Patient Outcome Questionnaire;Incidence of clinically significant respiratory depression events;

Countries

China

Contacts

Public ContactDr LAU Lai Ning Lydia

Chinese University of Hong Kong

lydialnlau@gmail.com+852 3505 3034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026