breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Pathologically diagnosed as invasive breast cancer; 2. Aged 18-70 years female; 3. Patients without any neoadjuvant therapy (including chemotherapy, radiotherapy and endocrine therapy); 4. Patients undergoing mastectomy and/or axillary dissection; 5. Subjects voluntarily joined the study and signed the informed consent, with good compliance and cooperative treatment.
Exclusion criteria
Exclusion criteria: 1. Known allergies to the drug or any of its excipients; 2. Patients with severe cardiovascular, digestive and endocrine diseases; 3. Human immunodeficiency virus (HIV) infection or known acquired immunodeficiency syndrome (AIDS), active hepatitis B (HBV DNA >=500 IU/ml), hepatitis C (hepatitis C antibody positive and HCV-RNA higher than the lower limit of assay) or co-infection with hepatitis B and C; 4. Patients undergoing or preoperatively anticoagulant therapy; 5. Patients with hereditary or acquired bleeding and thrombotic tendencies, such as hemophilia, clotting disorders, thrombocytopenia, and hypersplenism; 6. Patients with a history of psychiatric drug abuse or drug use; 7. Pregnant or lactating patients; 8. Patients with other serious physical or mental disorders or laboratory abnormalities that may increase the or interfere the results of the study, and patients that the investigator deems inappropriate for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volume of drainage;Retention time of drainage tube; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay post operation;drug safety;surgical safety; | — |
Countries
China
Contacts
The Fourth Affiliated Hospital of Hebei Medical University