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A clinical study for the technology based on two-demensional layer-specific strain echocardiology quantitative analysis on the effects of blood pressure variability on left ventricular systolic function in patients with primary hypertension

A clinical study for the technology based on two-demensional layer-specific strain echocardiology quantitative analysis on the effects of blood pressure variability on left ventricular systolic function in patients with primary hypertension

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000028716
Enrollment
Unknown
Registered
2020-01-01
Start date
2020-01-15
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Normal rhythm group:24-hour ambulate blood pressure monitoring
Abnormal rhythm group:24-hour ambulate blood pressure monitoring

Sponsors

Jiangsu Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 30-80 years; 2. Diagnosis of hypertension definitely; 3. Patients with untreated primary hypertension or patients who fail to meet standards; 4. Results of echocardiography: Simpson (biplane method) measured LVEF > 50%; 5. Sinus rhythm; 6. Informed consent, volunteer subjects.The process of obtaining informed consent shall comply with GCP requirements.

Exclusion criteria

Exclusion criteria: 1. Secondary hypertension caused by pheochromocytoma and nephritis; 2. Various cardiomyopathy; 3. Valvular disease; 4. Clear coronary heart disease; 5. Pericardial disease; 6. Severe liver, kidney and lung dysfunction; 7. Diabetes; 8. Persons with mental illness or severe mental symptoms; 9. Currently participating in clinical trials of other drugs; 10. Pregnant and nursing women; 11. Suspected or proven history of alcohol or drug abuse.

Design outcomes

Primary

MeasureTime frame
24hSBP;left ventricular endocardial longitudinal strain;left ventricular midcardial longitudinal strain;left ventricular epicardial longitudinal strain;

Countries

China

Contacts

Public ContactTao Weiwei

Jiangsu Provincial Hospital of Traditional Chinese Medicine

cherrytww@163.com+86 18724015082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026