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A multicenter, randomized, controlled trial for the analysis of the safety and effectiveness of Transurethral holmium laser enucleation of the prostate (HoLEP), Nd: YAG laser enucleation of the prostate and plasma bipolar enucleation of the prostate for the treatment of BPH

A multicenter, randomized, controlled trial for the analysis of the safety and effectiveness of Transurethral holmium laser enucleation of the prostate (HoLEP), Nd: YAG laser enucleation of the prostate and plasma bipolar enucleation of the prostate for the treatment of BPH

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028688
Enrollment
Unknown
Registered
2019-12-31
Start date
2020-02-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign prostatic hyperplasia

Interventions

Group A :Transurethral holmium laser enucleation of prostate
Group B :Transurethral Nd: YAG laser enucleation of prostate
Group C :Transurethral plasma bipolar prostatectomy

Sponsors

Renmin Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
55 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. The patients had clinical symptoms such as urgency of urination, increased nocturia and dysuria; 2. The examination of the digital rectum showed that the prostate became larger and stronger, and the central sulcus became shallow or disappeared; 3. Urinary tract obstruction under urodynamics; 4. IPSS > 10; 5. The subjects had no mental illness or language dysfunction, could understand the situation of this study and had signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with previous history of prostate cancer or positive results of prostate puncture; 2. Previous urethral injury and stricture; 3. The patients with lower urinary tract injury caused by previous urethra or transurethral operation, etc; 4. Taking anticoagulants such as aspirin, warfarin, dabigatran, rivasaban, apixaban, etc. for more than one week without stopping; 5. Blood system diseases and abnormal coagulation; 6. Combined with serious systemic diseases, heart disease, pulmonary insufficiency and important organ failure, it can not tolerate anesthesia or operation.

Design outcomes

Primary

MeasureTime frame
International Prostate Symptom Score; Quality of life score;Maximum urine flow rate (Qmax);residual urine volume (PVR);

Secondary

MeasureTime frame
Operation time;Bladder flushing time;Time with catheter;Prostate quality;hemoglobin;

Countries

China

Contacts

Public ContactLi Haoyong

Renmin Hospital of Wuhan University

haoyli5118@126.com+86 17764060728

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026