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A prospective randomized controlled trial for the effects of laparoscopic and non-laparoscopic surgery on pancreas islet function

A prospective randomized controlled trial for the effects of laparoscopic and non-laparoscopic surgery on pancreas islet function

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028686
Enrollment
Unknown
Registered
2019-12-30
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative metabolic dysfunction

Interventions

Group A:laparotomy operation
Group B:laparoscopic surgery

Sponsors

First Hospital Affiliated to Shandong first Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18~70 years old; 2. BMI 18~25; 3. the American society of anesthesiologists (ASA) class I, II; 4. The operation time is expected to be more than 1h for the patients who plan to undergo general anesthesia; 5. The patients has a good general condition and can tolerate surgery; 6. The patients with informed consent.

Exclusion criteria

Exclusion criteria: 1. Preoperative blood glucose is higher than 6.5mmol/L; 2. Use insulin and hypoglycemic drugs (In six months); 3. Received general anesthesia in three years; 4. Hypertension grade ii or above or serious organic heart disease; 5. Liver, renal insufficiency or failure; 6. Participated in other clinical researchers for nearly one year; 7. Suffering from serious mental or mental illness.

Design outcomes

Primary

MeasureTime frame
blood glucose;blood glucose;blood glucose;blood glucose;insulin;insulin;insulin;insulin;C-Peptide;C-Peptide;C-Peptide;C-Peptide;

Secondary

MeasureTime frame
Basic intraoperative vital signs;The results of laboratory tests before and after the operation;

Countries

China

Contacts

Public ContactWang Yuelan

First hospital affiliated to Shandong first Medical University

wyldgf@163.com+86 15953105780

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026