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Finding genetic polymorphisms of unexplained recurrent spontaneous abortion based on Whole exome sequencing

Finding genetic polymorphisms of unexplained recurrent spontaneous abortion based on Whole exome sequencing

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900028677
Enrollment
Unknown
Registered
2019-12-30
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Spontaneous Abortion

Interventions

unexplained recurrent spontaneous abortion:whole exome sequencing
Normal reproductive history couple:whole exome sequencing

Sponsors

The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Voluntary test and signing informed consent; 2. Couples aged 20-40 years; 3. Patients who had spontaneous abortion 2 times or more before 28 weeks.

Exclusion criteria

Exclusion criteria: 1. Patients who refused to sign an informed consent form to participate in the trial; 2. Hepatic and renal dysfunction; 3. Chromosomal abnormality in both husband and wife; 4. Endocrine abnormalities; 5. Reproductive system malformations; 6. Reproductive tract infection; 7. Autoimmune diseases; 8. Pre-thrombotic state factors 9. Immune abnormalities; 10. Male have DFI abnormalities; 11. Male have sex hormone abnormalities; 12. Male have varicocele; 13. Other internal surgery diseases.

Design outcomes

Primary

MeasureTime frame
Gene;—

Countries

China

Contacts

Public ContactKun Deng

The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital)

530460258@qq.com+86 15923800009

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026