Langerhans cell histiocytosis
Conditions
Interventions
Gold Standard:Pathological diagnosis
for 
diagnosis 
of 
with 
osteopontin 
combined 
MRI
Sponsors
Beijing Children’s Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed LCH; Diagnostic criteria: all patients required pathological results of lesion biopsy, CD1a positive and/or CD207 (Langerin) positive immunohistochemical staining; 2. Aged <18 years; 3. Children with craniofacial bone involvement or with pituitary MRI abnormalities; 4. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Received chemotherapy before; 2. Those who are allergic to the drugs used in the program; 3. Particicpated in other clinical researchers at the same time; 4. Patients have insufficiency cerebrospinal fluid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| osteopontin;IL-9;IL-2;IL-4;Interferon-Y;IL-10;IL-6;TNF a; | — |
Countries
China
Contacts
Public ContactNa Li
Beijing Children's Hospital, Capital Medical University
Outcome results
None listed