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A prospective, randomized, controlled trial for the safety and efficacy of different dosage sugammadex for reversal of rocuronium-induced deep neuromuscular blockade in morbidly obese patients undergoing Laparoscopic Bariatric Surgery

A prospective, randomized, controlled trial for the safety and efficacy of different dosage sugammadex for reversal of rocuronium-induced deep neuromuscular blockade in morbidly obese patients undergoing Laparoscopic Bariatric Surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028652
Enrollment
Unknown
Registered
2019-12-29
Start date
2019-12-20
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuromuscular Blockade

Interventions

B:Medication according to corrected body weight
C:No medication
A:Medication according to total body weight

Sponsors

The Fourth Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 60 years; 2. American Society of Anesthesiologists (ASA) physical status 1-3; 3. Patients with BMI>=40kg/m2 undergoing Laparoscopic Bariatric Surgery; 4. Agree to this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications for the use of aminosteroid muscle relaxants; 2. Patients with hepatic or renal dysfunction; 3. Known or suspected neuromuscular disease; 4. Taking medications that might influence the effect of NMB agents; 5. Allergy to Sugammadex or other General Anesthetics.

Design outcomes

Primary

MeasureTime frame
The time of TOF ratio to 0.9;All adverse events;

Secondary

MeasureTime frame
The time of TOF ratio to 0.8;The time of TOF ratio to 0.8;

Countries

China

Contacts

Public ContactChunming Yin

Department of Anesthesiology, The Fourth Affiliated Hospital of China Medical University

cmu4h_ycm@126.com+86 18900912998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 16, 2026