Catheter Related Bladder Discomfort
Conditions
Interventions
M group:Mirabegron 50mg
S group:Solifenacine
C group:Nil
Sponsors
Capital Medical University, Beijing Chaoyang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: a. Patients participate voluntarily. They are able to understand and comply with the scheme, as well as sign an informed consent form; b. The age of patient is between 18 and 75 years old, regardless of sex; c. Patients with indwelling catheter for more than 3 days after transurethral resection
Exclusion criteria
Exclusion criteria: 1. People with major diseases, including patients who may confuse the effectiveness of the evaluation (those who have participated in or are in the process of participating in other clinical trials within 3 months); 2. Patients with diseases with taboos in the use of anticholinergic drugs (such as urine retention, angle-closure glaucoma (untreated, uncontrolled intraocular pressure), paralytic intestinal obstruction, etc.); 3. Patients with obvious abnormal liver and kidney function (ALT, AST) are 2 times higher than the normal value, and the (Cr) of renal function is 1.5 times higher than the normal value. 4. Patients also use drugs that may affect detrusor activity, including anticholinergic drugs and tricyclic antidepressants. 5. Patients also use drugs that may affect the metabolism of the tested drugs, including fluoxetine and macrolide antibiotics. 6. Patients who consume too much caffeine (drinking more than five cups of coffee, tea or cola a day); 7. Those who have a history of alcohol or drug abuse in the last year; 8. People who are allergic to anticholinergic drugs 9. Patietns with systolic blood pressure >= 160mmHg or diastolic blood pressure >= 100 mmHg; 10. Patients with congenital or acquired prolonged QT interval. 11. Patients with Double J stent; 12. Pregnant women, lactating women, and patients planning to become pregnant; 13. Patients who are determined by the researchers to be unsuitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overactive Bladder Symptoms Score;Catheter-Related Bladder Discomfort; | — |
Countries
China
Contacts
Public ContactPeng Zhang
Capital Medical University, Beijing Chaoyang Hospital
Outcome results
None listed