Atrial fibrillation
Conditions
Interventions
Two groups:Cryoballoon Ablation Guided by threE-Dimensional mapping system versus RadioFrequency Catheter Ablation guided by index
Sponsors
Changhai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Symptomatic nonvalvular ward fibrillation, with ECG, DCG or random ECG evidence proving the onset of AF; 2. At least one class III antiarrhythmic drug is ineffective or intolerable; 3. Aged 18-80 years; 4. Patients understand the advantages and disadvantages of cryoablation and radiofrequency ablation; 5. The subjects or their legal representatives can understand and are willing to sign the informed consent to participate in the experiment.
Exclusion criteria
Exclusion criteria: 1. Thrombus formation in left atrium or left auricle; 2. Left atrium diameter > 50mm; 3. High risk of bleeding or contraindication of anticoagulant application; 4. Stroke or myocardial infarction within 3 months; 5. Uncontrolled hyperthyroidism; 6. Pregnancy; 7. Expected survival < 1 year; 8. Refuse to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1-year AF free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of serious complications; | — |
Countries
China
Contacts
Public ContactSongqun Huang
Changhai Hospital
Outcome results
None listed