Effects of SGLT2 inhibitors on urinary exosome miRNA in early type 2 diabetic nephropathy

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900028534

Enrollment

Unknown

Registered

2019-12-26

Start date

2020-01-01

Completion date

Unknown

Last updated

2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetic nephropathy

Interventions

Gold Standard:Clinical outcome

Index test:urinary&#32

exosomal&#32

miRNA

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-70 years WHO were diagnosed with type 2 diabetes according to WHO diagnostic criteria; 2. Healthy people selected 10 medical personnel with normal blood glucose, blood lipid, blood pressure, blood routine and urine routine in our hospital. 50 patients with type 2 diabetes who were screened for urinary microalbumin/creatinine at least three times.

Exclusion criteria

Exclusion criteria: Diabetic ketoacidosis or hyperosmolar hyperglycemia, glomerular filtration rate < 45ml/min/1.73m2), malignancy within 5 years, pregnancy or lactation, and failure to follow the study protocol

Design outcomes

Primary

Measure	Time frame
SEN, SPE, ACC, AUC of ROC;Urinary exosomal miRNA;	—

Contacts

Public ContactBai Feng

Huai'an Second People's Hospital

jiefu6887579@163.com+86 15189556566

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026