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A blood metabolomics study on the effects of repetitive transcranial magnetic stimulation on upper limb motor dysfunction after acute stroke.

A blood metabolomics study on the effects of repetitive transcranial magnetic stimulation on upper limb motor dysfunction after acute stroke.

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028519
Enrollment
Unknown
Registered
2019-12-25
Start date
2019-05-01
Completion date
Unknown
Last updated
2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Onset time <2 weeks; Aged 18-80 years old; CT or diffusion weighted magnetic resonance imaging (DWI) confirmed the presence of ischemic stroke; MRI lesions were located in the blood supply area of internal carotid artery. Adverse lateral limb movement; Muscle strength of the affected upper limb is grade 4/5; No serious aphasia or apraxia; Neglect, epilepsy; Sign the informed consent.

Exclusion criteria

Exclusion criteria: Do not use in patients with metal foreign body inside or outside the skull; Do not use pacemakers, medical pumps or cochlear implants, or increased intracranial pressure. Do not use in patients with recurrent or severe headache; High frequency strong stimulation has the risk of causing convulsion. High frequency strong stimulation is prohibited for patients with a history of epilepsy or a family history of epilepsy. Other diseases of the nervous or mental system;The cognitive dysfunction can't cooperate with the examination; It is not expected to complete the interview.

Design outcomes

Primary

MeasureTime frame
hemometabolomics;

Secondary

MeasureTime frame
motor evoked potential;Motor function assessment;Cognitive function assessment;

Countries

China

Contacts

Public ContactQi Fang, Qingmei Chen

Department of Neurology, the First Affiliated Hospital of Soochow University

fangqi_008@126.com+86 15850156612

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026